Publications
Peer-Reviewed Journals  |  Books Chapters  |  Selected Proceedings & Conference Papers


22.     K. Freedman, G Goyal, CW Ahn, MJ Kim. "Substrate Dependent Ad-Atom Migration on Graphene and the Impact on Electron-Beam Sculpting Functional Nanopores," Sensors, 17 (5), 1091.

21.    K. Freedman, C. Crick, P. Albella, A. Barik, A. Ivanov, S. Maier, S.H. Oh, J. Edel. "On-Demand Surface and Tip Enhanced Raman Spectroscopy Using Dielectrophoretic Trapping and Nanopore Sensors," ACS Photonics, 3(6), 1036-1044 (2016).

20.  K. Freedman, L. Otto, A. Ivanov, S. Oh, J. Edel, "Nanopore Sensing at Ultra-low Concentrations using Single Molecule Dielectrophoretic Trapping," Nature Communications, 7, 10217 (2016).

19.     K. Freedman*, S. R. Haq, J.B. Edel, P. Jemth, M.J. Kim*, "Nonequilibrium Capture Rates Induce Protein Accumulation and Enhanced Adsorption to Solid-State Nanopores," ACS Nano, 8 (12), 12238-12249 (2015).      * Co-Corresponding Author

18.     A. Rutkowska, K. Freedman, J. Skalkowska, M.J. Kim, J.B. Edel, and T. Albrecht, 2015, "Electrodeposition and Bipolar Effects in Metallized Nanopores and Their Use in the Detection of Insulin," Analytical Chemistry, 87 (4), 2337-2344 (2015).

17.    A.R. Bastian, et al., "Mechanism of Multivalent Nanoparticle Encounter with HIV-1 for Potency Enhancement of Peptide Triazole Inactivators," Journal of Biological Chemistry, 290(1), 529-543 (2014).

16.     A.P. Ivanov, K. Freedman, Min Jun Kim, T. Albrecht, J.B. Edel, "High precision fabrication and positioning of nanoelectrodes in a nanopore," ACS Nano, 8 (2), 1940-1948 (2014).

15.     K. Freedman, C.W. Ahn, M.J. Kim, "Detection of long and short DNA using nanopores with graphitic polyhedral edges," ACS Nano, 7(6), 5008-5016 (2013).

14.     G. Goyal, K. Freedman, M.J. Kim, "Gold nanoparticle translocation dynamics and electrical detection of single particle diffusion using solid state nanopores," Analytical Chemistry, 85(17), 8180-8187 (2013).

13.     A.R. Bastian, M. Contarino, F. Kantharaju, D. Moreira, K. Freedman, K. McFadden, C. Duffy, J. Jacobson, J. Hoxie, and I. Chaiken, "Molecular and Functional Transitions in the Virolytic Breakdown of HIV-1 by Sulfhydryl Peptide Triazole," Retrovirology, 10,153 (2013). 

12.     D. Japrung, J. Dogan, K. Freedman, A. Nadzeyka, S. Bauerdick, T. Albrecht, Min Jun Kim, P. Jemth, J. Edel, "Single molecule studies of intrinsically disordered proteins using solid-state nanopores," Analytical Chemistry, Vol. 85, No.4, p2449-2456 (2013).

11.     K. Freedman, S. R. Haq, J.B. Edel, P. Jemth, M.J. Kim, "Controlled unfolding and stretching of a protein domain inside a solid-state nanopore," Nature Scientific Reports, Vol. 3, 1638 (2013).

10.     K. Freedman, A. Bastian, I. Chaiken, M.J. Kim, "Solid-state nanopore detection of antibody-antigen complexes: a HIV model study," Small, 9(5), 750-759 (2013).   ***Selected for the front cover of Small***

9. W. Jo, K. Freedman, D.K. Yi, M.J. Kim, "Fabrication of tunable silica-mineralized nanotubes using flagella as bio-templates," Nanotechnology, Vol. 23, 055601 (2012).

8. A.S. Prabhu, K. Freedman, J.W.F. Robertson, Z. Nikolov, J.J. Kasianowicz, M.J. Kim, "SEM-induced shrinking of solid-state nanopores for single molecule detection," Nanotechnology, Vol. 22, 425302 (2011).

7. W. Jo, K. Freedman, D.K. Yi, R.K. Bose, K.K.S. Lau, S.D. Solomon, Min Jun Kim, "Photon to thermal response of single patterned gold nanorods cluster under near infrared laser irradiation," Biofabrication, Vol. 3, 015002 (2011).

6. W. Jo, K. Freedman, Min Jun Kim, "Metallization of biologically inspired silica nanotubes," Materials Science and Engineering: C, 32(8), 2426-2430 (2012).

5. K. Freedman, M. Jurgens, A. Prabhu, C.W. Ahn, P. Jemth, J. Edel, M.J. Kim, "Chemical, thermal, and electric field induced unfolding of single protein molecules studied using nanopores," Analytical Chemistry, Vol. 83, 5137-5144 (2011).

4. A. Prabhu, T. Jubery, K. Freedman, R. Mulero, P. Dutta, M. Kim. Chemically modified solid-state nanopores for high throughput nanoparticle separation.  Condensed Matter, 22 ,454107 (2010).

3. R. Mulero, A. Prabhu, K. Freedman, M. Kim, Nanopore Based Devices for Bioanalytical Applications, Journal of the Association for Laboratory Automation, 15(3): 243-252 (2010).

2.  K. Freedman, Jurgens, M., Peyman, S.A.,  Prabhu, A., Jemth, P., Edel, J., Min Jun Kim, "Single molecule protein biophysics using chemically modified nanopores," Sensors IEEE, 1060-1065 (2010). 

1. W. Hesse, K. Freedman, M.J. Kim. The importance of bacterial nanofluidics on medicine and engineering. Small, 6(8), 895-909 (2010).


Book Chapters
1.  K. Freedman, M.J. Kim, " Single Molecule Protein Unfolding Using a Nanopore," in Nanofluidics (2nd Edition), Ed. J.B. Edel and T. Albrecht, Royal Society of Chemistry, 2016. (In Press). 

2. G. Goyal, K. Freedman, A.S. Prabhu, M.J. Kim, "Case Studies Using Solid State Pores," in Engineered Nanopores for Bioanalytical Applications, Ed. J.B. Edel and T. Albrecht, Elsevier, 2013.

3. K. Freedman.  Seizure detection using a novel multi-measurement support vector machine algorithm, Lap Lambert Publishing, 2009.

4.  Acknowledged in the following: Chronobioengineering: Introduction to Biological Rhythms with Applications, Morgan and Claypool Publishers, 2012.






Proceedings and Conference Papers
K. Freedman, L. Otto, A. Ivanov, S. Oh, J. Edel, "Nanopore Sensing at Ultra-low Concentrations using Single Molecule Dielectrophoretic Trapping," The EMN Meeting, Istanbul, Turkey, 2015.  Invited Speaker

K. Freedman, A. Ivanov, J. Edel, "Functionalized nanopores for single molecule delivery, temperature control, and SERRS detection", Swiss Nanopore, Switzerland, 2015. Invited Speaker

K. Freedman, C.W. Ahn, Min Jun Kim, "Graphite polyhedral crystal formation at the nanopore edge and its favorable interactions with single stranded DNA," The 245th ACS National Meeting and Exposition, New Orleans, LA, U.S.A., 2013.

K. Freeman, A. Prabhu, P. Jemth, J. Edel, Min Jun Kim, "Protein unfolding and stability measurement using a solid-state nanopore," The 56th Annual Biophysical Society Meeting, San Diego, CA, U.S.A., 2012.

W. Jo, K. Freedman, Min Jun Kim, "Characterization of flagella-templated silica nanotubes and their metallization," The 38th Annual Northeast Bioengineering Conference, Philadelphia, PA, U.S.A., 2012.

K. Freedman, J.B. Edel, P. Jemth, Min Jun Kim, "Single Molecule Protein Folding Kinetics using Solid-State Nanopores," 12th HFSP Awardees Meeting, Daegu, Korea, July 2012.

A.R. Bastian, M. Contarino, F. Kantharaju, D. Moreira, K. Freedman, K. McFadden, C. Duffy, J. Jacobson, J. Hoxie, and I. Chaiken, "Molecular and Functional Transitions in the Virolytic Breakdown of HIV-1", Annual Conference on Retroviruses and Opportunistic Infections, Boston, MA, March, 2012.

K. Freedman, R. Bastian, A. Prabhu, C.W. Ahn, I. Chaiken, Min Jun Kim, "Nanopore-based detection of protein complexes: an HIV antigen model study," The Nanopores Conference, Puerto Calero, Lanzarote, Spain, 2012.

K. Freedman, C.W. Ahn, J. Edel, P. Jemth, Min Jun Kim, "Protein unfolding kinetics inside a solid-state nanopore," The Nanopores Conference, Puerto Calero, Lanzarote, Spain, 2012.

K. Freedman, R. Haq, M. Jurgens, R. Mulero, A. Prabhu, P. Jemth, J. Edel, Min Jun Kim, "Chemical and electric field unfolding effects inside a nanopore: a single molecule study," MicroTas, Seattle, USA, 0591, 2011.

W. Jo, K. Freedman, D.K. Yi, Min Jun Kim, "Fabrication of flagella-templated silica nanotubes," The US-Korea Conference on Science, Technology, and Entrepreneurship, Park City, UT, U.S.A., G.3, 2011.

K. Freedman, C.W. Ahn, J. Edel, P. Jemth, Min Jun Kim, "Studying Proteins at the Single Molecule Level Using Nanopore Technology", Asia Nano Meeting, Daejeon, South Korea, 2011. Invited Speaker

W. Jo, K. Freedman, K. Rizzo, S.D. Solomon, Min Jun Kim, "Using photon-to-thermal characteristics of gold nanorods to biofilm disinfection," The US-Korea Conference on Science, Technology, and Entrepreneurship, Seattle, WA, U.S.A.

K. Freedman, M. Jurgens, S.A. Peyman, A. Prabhu, P. Jemth, J. Edel, Min Jun Kim, "Single molecule protein biophysics using chemically modified nanopores," The IEEE Sensors Conference, Waikoloa, HI, 1818, 2010.

K. Freedman, R. Haq, M. Jurgens, R. Mulero, A. Prabhu, P. Jemth, J. Edel, Min Jun Kim, "Solid-state nanopore analysis of the PDZ2 protein domain," The APS March Meeting, Portland, Oregon, A10.00008, 2010.

A.S. Prabhu, T.Z. Jubery, K. Freedman, R. Mulero, P. Dutta, Min Jun Kim, "High throughput nanofluidic architectures for nanoparticle separation ," 2009 ASME IMECE, Lake Buena Vista, FL, IMECE2009-10649, 2009. Recipient of the "Best Paper Award" in the 2009 ASME Microfluidics Symposium

K. Freedman, R. Haq, M. Jurgens, A. Prabhu, P. Jemth, J. Edel, Min Jun Kim, "Solid-state nanopore analysis of the PDZ2 protein domain ," NSF IGERT Project Meeting, Washington DC, 2010.

K. Freedman, D. Grasse, K. Moxon, "A Quantitative Analysis of Brain Signals from the Kainic-Acid Epilepsy Model", Drexel University Biomedical Engineering Entrepreneur and Technical Showcase, Philadelphia, PA, 2009. 

K. Freedman, D. Grasse, K. Moxon, "A Quantitative Analysis of Brain Signals from the Kainic-Acid Epilepsy Model", Northeastern Bioengineering Conference, Providence, RI, 2008. 

K. Freedman, D. Grasse, K. Moxon, "A Multi-Dimensional Seizure Detection Algorithm Using Support Vector Machines", Drexel University Research Day 2008, Philadelphia, PA, 2008. 

D. Grasse, K. Freedman, K. Moxon,  "Using single neuron recording to understand seizure generation", Drexel University Research Day 2008, Philadelphia, PA, 2008. 






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