Publications

Since Joining UCR

• Published in ACS Sensors

  • • • • Protein and DNA Yield Current Enhancements, Slow Translocations, and an Enhanced Signal-to-Noise Ratio under a Salt Imbalance | ACS Sensors

• Published in Nature Communications

  • • • • On the origins of conductive pulse sensing inside a nanopore | Nature Communications

• Published in JACS

  • • • • Nanopore Current Enhancements Lack Protein Charge Dependence and Elucidate Maximum Unfolding at Protein’s Isoelectric Point | Journal of the American Chemical Society (acs.org)

• Published in SMALL

  • • • • DNA Coil Dynamics and Hydrodynamic Gating of Pressure‐Biased Nanopores - Sharma - 2022 - Small - Wiley Online Library

• Published in ACS Nano

  • • • • Pressure-Biased Nanopores for Excluded Volume Metrology, Lipid Biomechanics, and Cell-Adhesion Rupturing | ACS Nano

• Published in NanoLetters

  • • • • Constricted Apertures for Dynamic Trapping and Micro-/Nanoscale Discrimination Based on Recapture Kinetics | Nano Letters(acs.org)

• Published in Frontiers in Nanotechnology

  • • • • Frontiers | Calibration-Less DNA Concentration Measurements Using EOF Volumetric Flow and Single Molecule Counting | Nanotechnology(frontiersin.org)

• Published in Nanoscale

  • • • • Measuring trapped DNA at the liquid-air interface for enhanced single molecule sensing - Nanoscale (RSC Publishing)

• Published in Nanomedicine: Nanotechnology, Biology and Medicine

  • • • • Nanodiagnostics: A review of the medical capabilities of nanopores - ScienceDirect

• [Pre-Print] The Origin of Conductive-Pulse Sensing Inside a Nanopore and the Role of Electro-Hydrodynamics

  • • • • The Origin of Conductive-Pulse Sensing Inside a Nanopore and the Role of Electro-Hydrodynamics (biorxiv.org)

• Published in Sensors

  • • • • Sensors | Free Full-Text | Substrate Dependent Ad-Atom Migration on Graphene and the Impact on Electron-Beam Sculpting Functional Nanopores (mdpi.com)

Prior to Joining UCR

• K. Freedman, C. Crick, P. Albella, A. Barik, A. Ivanov, S. Maier, S.H. Oh, J. Edel. "On-Demand Surface and Tip Enhanced Raman Spectroscopy Using Dielectrophoretic Trapping and Nanopore Sensors," ACS Photonics, 3(6), 1036-1044 (2016).

• K. Freedman, L. Otto, A. Ivanov, S. Oh, J. Edel, "Nanopore Sensing at Ultra-low Concentrations using Single Molecule Dielectrophoretic Trapping," Nature Communications, 7, 10217 (2016).

• K. Freedman*, S. R. Haq, J.B. Edel, P. Jemth, M.J. Kim*, "Nonequilibrium Capture Rates Induce Protein Accumulation and Enhanced Adsorption to Solid-State Nanopores," ACS Nano, 8 (12), 12238-12249 (2015). * Co-Corresponding Author

• A. Rutkowska, K. Freedman, J. Skalkowska, M.J. Kim, J.B. Edel, and T. Albrecht, 2015, "Electrodeposition and Bipolar Effects in Metallized Nanopores and Their Use in the Detection of Insulin," Analytical Chemistry, 87 (4), 2337-2344 (2015).

• A.R. Bastian, et al., "Mechanism of Multivalent Nanoparticle Encounter with HIV-1 for Potency Enhancement of Peptide Triazole Inactivators," Journal of Biological Chemistry, 290(1), 529-543 (2014).

• A.P. Ivanov, K. Freedman, Min Jun Kim, T. Albrecht, J.B. Edel, "High precision fabrication and positioning of nanoelectrodes in a nanopore," ACS Nano, 8 (2), 1940-1948 (2014).

• K. Freedman, C.W. Ahn, M.J. Kim, "Detection of long and short DNA using nanopores with graphitic polyhedral edges," ACS Nano, 7(6), 5008-5016 (2013).

• G. Goyal, K. Freedman, M.J. Kim, "Gold nanoparticle translocation dynamics and electrical detection of single particle diffusion using solid state nanopores," Analytical Chemistry, 85(17), 8180-8187 (2013).

• A.R. Bastian, M. Contarino, F. Kantharaju, D. Moreira, K. Freedman, K. McFadden, C. Duffy, J. Jacobson, J. Hoxie, and I. Chaiken, "Molecular and Functional Transitions in the Virolytic Breakdown of HIV-1 by Sulfhydryl Peptide Triazole," Retrovirology, 10,153 (2013).

• D. Japrung, J. Dogan, K. Freedman, A. Nadzeyka, S. Bauerdick, T. Albrecht, Min Jun Kim, P. Jemth, J. Edel, "Single molecule studies of intrinsically disordered proteins using solid-state nanopores," Analytical Chemistry, Vol. 85, No.4, p2449-2456 (2013).

• K. Freedman, S. R. Haq, J.B. Edel, P. Jemth, M.J. Kim, "Controlled unfolding and stretching of a protein domain inside a solid-state nanopore," Nature Scientific Reports, Vol. 3, 1638 (2013).

• K. Freedman, A. Bastian, I. Chaiken, M.J. Kim, "Solid-state nanopore detection of antibody-antigen complexes: a HIV model study," Small, 9(5), 750-759 (2013). ***Selected for the front cover of Small***

• W. Jo, K. Freedman, D.K. Yi, M.J. Kim, "Fabrication of tunable silica-mineralized nanotubes using flagella as bio-templates," Nanotechnology, Vol. 23, 055601 (2012).

• A.S. Prabhu, K. Freedman, J.W.F. Robertson, Z. Nikolov, J.J. Kasianowicz, M.J. Kim, "SEM-induced shrinking of solid-state nanopores for single molecule detection," Nanotechnology, Vol. 22, 425302 (2011).

• W. Jo, K. Freedman, D.K. Yi, R.K. Bose, K.K.S. Lau, S.D. Solomon, Min Jun Kim, "Photon to thermal response of single patterned gold nanorods cluster under near infrared laser irradiation," Biofabrication, Vol. 3, 015002 (2011).

• W. Jo, K. Freedman, Min Jun Kim, "Metallization of biologically inspired silica nanotubes," Materials Science and Engineering: C, 32(8), 2426-2430 (2012).

• K. Freedman, M. Jurgens, A. Prabhu, C.W. Ahn, P. Jemth, J. Edel, M.J. Kim, "Chemical, thermal, and electric field induced unfolding of single protein molecules studied using nanopores," Analytical Chemistry, Vol. 83, 5137-5144 (2011).

• A. Prabhu, T. Jubery, K. Freedman, R. Mulero, P. Dutta, M. Kim. Chemically modified solid-state nanopores for high throughput nanoparticle separation. Condensed Matter, 22 ,454107 (2010).

• R. Mulero, A. Prabhu, K. Freedman, M. Kim, Nanopore Based Devices for Bioanalytical Applications, Journal of the Association for Laboratory Automation, 15(3): 243-252 (2010).

• K. Freedman, Jurgens, M., Peyman, S.A., Prabhu, A., Jemth, P., Edel, J., Min Jun Kim, "Single molecule protein biophysics using chemically modified nanopores," Sensors IEEE, 1060-1065 (2010).

• W. Hesse, K. Freedman, M.J. Kim. The importance of bacterial nanofluidics on medicine and engineering. Small, 6(8), 895-909 (2010).